(A) The indicated strains of C. albicans were incubated with the FaDu oral epithelial cell line for 90 min, after which the numbers of endocytosed and cell-associated organisms were determined by a differential fluorescence assay. (B) The indicated host cells were loaded with 51Cr and then incubated with the indicated strains of C. albicans for 3 h. The extent of host cell damage was measured by the release of 51Cr into the medium. Results are the mean standard deviation of three experiments, each performed in triplicate. Data are represented as mean ± SD (n=3), and statistical significance relative to wild-type is indicated (*, p<0.05; **, p<0.01; ***, p<0.001).