Table 1.
Sham | Burn | ||||
---|---|---|---|---|---|
Analyte | Vehicle | Bo | Vehicle | Early-Bo | Late-Bo |
Total protein (mg/dL) | 2.14 ± 0.73 | 3.05 ± 1.09 | 4.68 ± 1.41 | 4.56 ± 1.33 | 4.32 ± 1.16 |
Cholesterol (mg/dL) | 215.70 ± 13.45 | 198.60 ± 46.25 | 172.70 ± 47.76 | 203.71 ± 19.96 | 211.00 ± 12.65 |
Glucose (mg/dL) | 221.70 ± 40.08 | 243.70 ± 54.86 | 259.00 ± 58.07 | 205.60 ± 18.34 | 231.10 ± 56.29 |
Na (mM) | 142.30 ± 2.08 | 141.70 ± 1.76 | 143.50 ± 2.34 | 141.90 ± 2.53 | 142.80 ± 1.49 |
Creatinine (mg/dL) | 0.22 ± 0.04 | 0.22 ± 0.06 | 0.20 ± 0.00 | 0.21 ± 0.04 | 0.20 ± 0.00 |
BUN (mg/dL) | 19.00 ± 2.99 | 20.65 ± 4.34 | 19.44 ± 2.19 | 23.50 ± 4.07 | 21.83 ± 3.02 |
GGT (U/L) | 189.30 ± 60.37 | 215.90 ± 81.85 | 196.30 ± 91.29 | 247.40 ± 28.45 | 257.29 ± 42.92 |
ALT (U/L) | 101.80 ± 22.12 | 103.80 ± 21.15 | 76.13 ± 23.58 | 114.86 ± 26.19 | 108.86 ± 32.27 |
ALP (U/L) | 482.60 ± 38.66 | 464.60 ± 44.96 | 416.60 ± 176.10 | 539.83 ± 80.74 | 535.71 ± 84.15 |
WBC (103/mL) | 12.29 ± 2.93 | 12.69 ± 3.13 | 14.79 ± 6.13 | 14.19 ± 1.94 | 17.34 ± 1.82 |
HGB (g/dL) | 13.76 ± 1.10 | 13.55 ± 1.26 | 13.64 ± 1.14 | 12.66 ± 0.36 | 12.71 ± 0.72 |
HCT (%) | 39.03 ± 2.30 | 37.56 ± 4.29 | 37.41 ± 3.31 | 34.83 ± 2.79 | 34.87 ± 1.60 |
PLT (103/mL) | 334.10 ± 183.50 | 453.10 ± 189.30 | 618.40 ± 170.90 | 485.90 ± 341.80 | 519.90 ± 239.10 |
pH | 7.39 ± 0.20 | 7.37 ± 0.11 | 7.34 ± 0.13 | 7.37 ± 0.12 | 7.34 ± 0.14 |
PO2 (mmHg) | 427.80 ± 204.60 | 364.10 ± 207.30 | 530.30 ± 96.98 | 388.40 ± 257.20 | 441.90 ± 151.00 |
HCO3 (mmol/L) | 33.80 ± 2.30 | 34.54 ± 1.80 | 33.80 ± 2.30 | 33.29 ± 3.20 | 32.76 ± 2.30 |
BE (mEq/L) | 8.67 ± 4.38 | 9.17 ± 1.95 | 7.90 ± 2.98 | 7.84 ± 4.66 | 6.46 ± 3.16 |
Bo: Bortezomib. BUN: blood urea nitrogen. GGT:gamma-glutamyltranspeptidase. ALT: alanine aminotransferase. ALP: alkaline phosphatase. WBC: white blood cell count. HGB: hemoglobin. HCT: hematocrit. PLT: platelets. BE: base excess.
There were no statistically significant differences among the groups.