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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: Dev Biol. 2015 Jul 21;415(2):383–390. doi: 10.1016/j.ydbio.2015.07.018

Fig. 4.

Fig. 4

Cadherin-11 extracellular repeats 1 and 2 are sufficient to stimulate CNC migration in vivo. (A) Histogram representing the percentage of embryos with no migration due to the overexpression of C11, normalized to RFP. Rescue of migration requires co-expression of the artificial C11 cleavage fragment containing at least extracellular repeats 1 and 2 (EC1-2), while EC1 alone is not sufficient. (B) Representative images of embryos in (A) are shown with arrowheads pointing to RFP-labeled cells that successfully migrated into the branchial and hyoid arches. n=number of embryos scored from three independent experiments. Error bars are standard deviation to the mean. A Student's t-test was performed for significance to C11 overexpression. * < 0.05, *** < 0.005. Scale bar, 500 μm.