Table 2.
Associations with therapeutic decision (DES vs BMS)
| All patients | Patients with stable CAD | Patients with unstable CAD | |||||||
|---|---|---|---|---|---|---|---|---|---|
| DES (%)/ OR | N | p value | DES (%)/ OR | N | p value | DES (%)/ OR | N | p value | |
| Overall | 66 % | 442 | 66 % | 358 | 68 % | 84 | |||
| Diagnosis | 0.558 | ||||||||
| Stable CAD | 66 % | 358 | |||||||
| Unstable angina | 63 % | 46 | |||||||
| NSTEMI | 74 % | 38 | |||||||
| Hospital | p < 0.001 | p < 0.001 | p < 0.001 | ||||||
| 1 | 50 % | 130 | 52 % | 99 | 45 % | 31 | |||
| 2 | 64 % | 98 | 66 % | 87 | 55 % | 11 | |||
| 3 | 99 % | 81 | 98 % | 50 | 100 % | 31 | |||
| 4 | 64 % | 133 | 65 % | 122 | 55 % | 11 | |||
| Baseline characteristics | |||||||||
| Age (years) | 1.008 | 442 | 0.387 | 1.005 | 358 | 0.682 | 1.023 | 84 | 0.272 |
| Gender | 0.474 | 0.46 | 0.872 | ||||||
| Male | 67 % | 318 | 67 % | 261 | 68 % | 57 | |||
| Female | 64 % | 124 | 63 % | 97 | 67 % | 27 | |||
| SBP (mmHg) | 1.007 | 442 | 0.188 | 1.003 | 358 | 0.598 | 1.022 | 84 | 0.074 |
| DBP (mmHg) | 0.998 | 442 | 0.815 | 0.997 | 358 | 0.767 | 1.001 | 84 | 0.968 |
| BMI (kg/m 2) | 1.038 | 442 | 0.128 | 1.049 | 358 | 0.08 | 0.994 | 84 | 0.912 |
| TIMI scorea | 0.085 | 0.085 | |||||||
| 1 | 71 % | 7 | 71 % | 7 | |||||
| 2 | 80 % | 15 | 80 % | 15 | |||||
| 3 | 48 % | 25 | 48 % | 25 | |||||
| 4 | 83 % | 23 | 83 % | 23 | |||||
| 5 | 60 % | 10 | 60 % | 10 | |||||
| 6 + 7 | 100 % | 3 | 100 % | 3 | |||||
| NYHA | p < 0.01 | 0.036 | 0.011 | ||||||
| NYHA I | 62 % | 324 | 63 % | 260 | 59 % | 64 | |||
| NYHA II | 71 % | 79 | 69 % | 73 | 100 % | 6 | |||
| NYHA III & IV | 90 % | 39 | 88 % | 25 | 93 % | 14 | |||
| Number of diseased vessels | p < 0.01 | p < 0.01 | 0.102 | ||||||
| 1 | 58 % | 196 | 58 % | 166 | 57 % | 30 | |||
| > 1 | 73 % | 246 | 72 % | 192 | 74 % | 54 | |||
| Cardiac history | |||||||||
| Previous heart failure | 0.981 | 0.836 | 0.489 | ||||||
| Yes | 67 % | 9 | 63 % | 8 | 100 % | 1 | |||
| No | 66 % | 433 | 66 % | 350 | 67 % | 83 | |||
| Previous MI | 0.077 | 0.090 | 0.536 | ||||||
| Yes | 72 % | 137 | 72 % | 118 | 74 % | 19 | |||
| No | 64 % | 305 | 63 % | 240 | 66 % | 65 | |||
| Previous PTCA | p < 0.01 | p < 0.01 | 0.271 | ||||||
| Yes | 76 % | 148 | 76 % | 126 | 77 % | 22 | |||
| No | 61 % | 294 | 60 % | 232 | 65 % | 62 | |||
| Previous CABG | 0.541 | 0.736 | 0.433 | ||||||
| Yes | 61 % | 31 | 63 % | 27 | 50 % | 4 | |||
| No | 67 % | 411 | 66 % | 331 | 69 % | 80 | |||
| Non-cardiac history | |||||||||
| CVA/TIA | 0.748 | 0.682 | 0.924 | ||||||
| Yes | 69 % | 35 | 70 % | 23 | 67 % | 12 | |||
| No | 66 % | 407 | 66 % | 335 | 68 % | 72 | |||
| Pulmonary disease | 0.103 | 0.142 | 0.445 | ||||||
| Yes | 56 % | 47 | 55 % | 35 | 58 % | 12 | |||
| No | 68 % | 395 | 36 % | 323 | 69 % | 72 | |||
| PVD | 0.086 | 0.124 | 0.445 | ||||||
| Yes | 56 % | 57 | 56 % | 45 | 58 % | 12 | |||
| No | 68 % | 385 | 67 % | 313 | 69 % | 72 | |||
| Renal failure | 0.059 | 0.126 | 0.144 | ||||||
| Yes | 43 % | 14 | 46 % | 13 | 0 % | 1 | |||
| No | 67 % | 428 | 67 % | 345 | 69 % | 83 | |||
| Risk factors | |||||||||
| Diabetes mellitus | p < 0.001 | p < 0.001 | 0.009 | ||||||
| Yes | 93 % | 95 | 92 % | 78 | 94 % | 17 | |||
| No | 59 % | 347 | 59 % | 280 | 61 % | 67 | |||
| Hypertension | 0.306 | 0.498 | 0.324 | ||||||
| Yes | 68 % | 290 | 67 % | 240 | 72 % | 50 | |||
| No | 63 % | 152 | 63 % | 118 | 62 % | 34 | |||
| Hyperlipidaemia | 0.943 | 0.427 | 0.144 | ||||||
| Yes | 66 % | 302 | 65 % | 252 | 74 % | 50 | |||
| No | 67 % | 140 | 69 % | 106 | 59 % | 34 | |||
| Current smokers | 0.037 | 0.066 | 0.246 | ||||||
| Yes | 57 % | 85 | 55 % | 58 | 59 % | 27 | |||
| No | 69 % | 357 | 68 % | 300 | 72 % | 57 | |||
| Pack yearsb | 1.001 | 442 | 0.898 | 1.000 | 358 | 0.974 | 1.002 | 84 | 0.877 |
BMI body mass index, CABG coronary artery bypass graft, CAD coronary artery disease, CVA cerebrovascular accident, DBP diastolic blood pressure, MI myocardial infarction, NA not applicable, NSTEMI non ST elevation myocardial infarction, NYHA New York heart association, PTCA percutaneous transluminal coronary angioplasty, PVD peripheral vessel disease, SBP systolic blood pressure, TIA transient ischaemic attack, TIMI thrombolysis in myocardial infarction.
aonly for unstable angina and NSTEMI.
bNumber of packs per day multiplied with years of smoking.