Table 3.
Comparison of responders (n = 20) and non-responders (n = 21) | ||||
---|---|---|---|---|
Responder | Non-responder | |||
BASELINE | ||||
Y-BOCS total score | 25.15 (±6.21) | 25.43 (±5.49) | p = 0.880 t = 0.15 | |
Y-BOCS compulsions | 11.80 (±4.20) | 11.86 (±3.47) | p = 0.962 t = 0.05 | |
Y-BOCS obsessive thoughts | 13.35 (±2.96) | 13.57 (±2.64) | p = 0.802 t = 0.25 | |
HAMD-17 | 13.90 (±6.55) | 11.65 (±5.53) | p = 0.248 t = 1.18 | |
MOCI | 12.61 (±4.63) | 13.83 (±3.92) | p = 0.399 t = 0.86 | |
BDI | 15.21 (±8.31) | 19.44 (±8.73) | p = 0.140 t = 1.51 | |
AFTER 10 WEEKS TREATMENT | ||||
Y-BOCS total score | 8.30 (±4.04) | 20.29 (±6.09) | p = 0.000 t = 7.39 | |
Y-BOCS compulsions | 3.90 (±2.17) | 9.43 (±3.71) | p = 0.000 t = 5.86 | |
Y-BOCS obsessive thoughts | 4.40 (±2.44) | 10.86 (±2.94) | p = 0.000 t = 7.64 | |
HAMD-17 | 8.30 (±7.40) | 10.00 (±6.85) | p = 0.456 t = 0.75 | |
MOCI | 7.06 (±5.18) | 11.18 (±6.17) | p = 0.043 t = 2.11 | |
BDI | 10.11 (±12.37) | 17.78 (±12.17) | p = 0.069 t = 1.88 | |
DIFFERENCE BASELINE—WEEK 10 | ||||
Y-BOCS total score | 16.85 (±5.82) | 5.14 (±4.91) | p = 0.000 t = 6.97 | |
Y-BOCS compulsions | 7.90 (±3.60) | 2.43 (±3.14) | p = 0.000 t = 5.20 | |
Y-BOCS obsessive thoughts | 8.95 (±3.52) | 2.71 (±2.76) | p = 0.000 t = 6.33 | |
HAMD-17 | 5.60 (±5.69) | 1.47 (±7.53) | p = 0.063 t = 1.92 | |
MOCI | 5.93 (±5.42) | 2.87 (±2.75) | p = 0.064 t = 1.96 | |
BDI | 5.71 (±11.37) | 2.65 (±8.62) | p = 0.384 t = 0.88 |