Table 1.

Relative expression of GNB isoforms in different shRNA-transduced HL60 cell lines

	GNB1 (SD)	GNB2 (SD)	GNB4 (SD)	GNB5 (SD)
shGNB1	0.37 (± 0.15)*	1.13 (± 0.19)	1.07 (± 0.28)	1.19 (± 0.06)
shGNB2	1.46 (± 0.29)	0.05 (± 0.01)*	0.89 (± 0.13)	0.93 (± 0.11)
shGNB4	1.14 (± 0.08)	1.29 (± 0.09)	0.12 (± 0.02)*	1.27 (± 0.21)
shGNB5	1.15 (± 0.16)	1.02 (± 0.17)	0.95 (± 0.11)	0.10 (± 0.03)*

Values indicate x-fold induction of the expression of the respective molecules in comparison with cells transduced with a nonsilencing scrambled construct. Expression levels were evaluated in a quantitative reverse-transcription polymerase chain reaction using gene-specific primer and probes (n = 4 experiments).

SD, standard deviation.

^*P < .05 vs gene expression in scrambled cells.