Table 1. The Association between Preoperative NLR and PLR Values and the Clinicopathological Characteristics of Papillary Thyroid Cancer.
| Characteristic | Patients, n (%) | NLR | PLR | ||
|---|---|---|---|---|---|
| Median (IQR) | P value | Median (IQR) | P value | ||
| Age, yr | 0.001 | <0.001 | |||
| <45 | 324 (30.4) | 1.75 (1.03-2.31) | 135.60 (91.00-163.06) | ||
| ≥45 | 742 (69.6) | 1.52 (1.16-2.00) | 123.60 (99.32-151.42) | ||
| Tumor size, cm | 0.522 | 0.021 | |||
| ≤1 | 774 (75.6) | 1.59 (1.20-2.06) | 124.41 (103.13-155.09) | ||
| >1 | 292 (27.4) | 1.53 (1.22-2.12) | 129.17 (106.24-162.44) | ||
| T stage | 0.370 | 0.801 | |||
| 1/2 | 944 (88.6) | 1.57 (1.21-2.08) | 125.62 (104.05-156.11) | ||
| 3/4 | 122 (11.4) | 1.63 (1.20-2.13) | 127.70 (97.84-156.75) | ||
| LNM | 0.634 | 0.765 | |||
| N0 | 432 (40.5) | 1.57 (1.19-2.07) | 125.59 (103.28-156.72) | ||
| N1 | 634 (59.5) | 1.68 (1.34-2.24) | 132.10 (114.12-149.81) | ||
| Multifocality | 0.483 | 0.526 | |||
| Negative | 746 (70) | 1.60 (1.23-2.11) | 126.06 (105.58-156.75) | ||
| Positive | 320 (30) | 1.53 (1.16-2.04) | 126.50 (99.35-154.50) | ||
| Hashimoto's thyroiditis | 0.005 | 0.039 | |||
| Negative | 940 (88.2) | 1.58 (1.21-2.11) | 127.61 (104.89-157.38) | ||
| Positive | 126 (11.8) | 1.52 (1.18-1.89) | 119.48 (94.02-147.48) | ||
| ETE | 0.185 | 0.805 | |||
| Negative | 654 (61.4) | 1.59 (1.20-2.08) | 124.31 (103.27-157.95) | ||
| Positive | 412 (38.6) | 1.57 (1.22-2.10) | 128.09 (106.15-154.26) | ||
| Lateral LNM | 0.101 | 0.316 | |||
| Negative | 1,001 (93.9) | 1.57 (1.19-2.07) | 125.59 (103.28-156.72) | ||
| Positive | 65 (6.1) | 1.68 (1.34-2.24) | 132.10 (114.38-148.46) | ||
| LVI | 0.155 | 0.400 | |||
| Negative | 524/715 (73.3) | 1.58 (1.21-2.04) | 126.96 (103.58-157.59) | ||
| Positive | 191/715 (26.7) | 1.52 (1.13-2.22) | 130.18 (104.77-158.92) | ||
| BRAF V600E mutation | 0.896 | 0.658 | |||
| Negative | 383/1,003 (38.2) | 1.58 (1.17-2.08) | 125.96 (101.57-154.28) | ||
| Positive | 620/1,003 (61.8) | 1.57 (1.23-2.10) | 125.68 (103.93-156.72) | ||
Statistical significance was tested by the Student t test.
NLR, neutrophil-to-lymphocyte count ratio; PLR, platelet-to-lymphocyte count ratio; IQR, interquartile range; LNM, lymph node metastasis; ETE, extrathyroidal extension; LVI, lymphovascular invasion.