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. 2016 Jan 15;33(2):175–182. doi: 10.1089/neu.2015.3887

FIG. 3.

FIG. 3.

COG1410 reduced lesion volume after controlled cortical impact (CCI). Representative T 2 maps were shown for the entire CCI lesion volume of a vehicle-treated and a COG1410-treated mouse pre- and post-CCI at Day 1 and Day 3 (A). The lesion volumes in COG1410-treated mice compared with vehicle-treated mice at Day 1 and Day 3 post-CCI are plotted (B). The results demonstrated that the lesion volume was markedly reduced by COG1410 treatment at Day 1 and Day 3 post-CCI. Veh, vehicle-treated mice; COG, COG1410-treated mice; D, day post-CCI. mean±standard error of the mean. n=5 per group. *p<0.05, **p<0.01, COG1410 group vs. vehicle group.