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. 2016 Jan 4;5:2. [Version 1] doi: 10.12688/f1000research.7628.1

Table 1. Comparison of specifications of three different types of eLNs.

Note that ease of use and the availability as well as power of features of eLNs are inversely related.

Basic systems, such as repurposed
word processors (e.g. Word) or note
taking systems (e.g. Evernote)
Dedicated, commercial eLNs (e.g.
iLabber, Labfolder, eCat)
High end systems (eLNs including a
LIMS, e.g. IBDS E-WORKBOOK, iLAB
Laboratory Execution System)
Ability to enter text as in conventional
handwritten LN
All features from the basic systems plus
(see below)
All features from the dedicated,
commercial systems plus (see below)
Notes can be made available on
multiple devices (stored in the cloud)
Freehand drawing Inventory management:

complete tracking of samples/reagents
through all experiments
Attach files to notes Complex rights management (with roles
and individual rights)
Workflows for certain samples, tasks,
experiments
Visualization of attachments in the note 21CFR 11 compliance:

All previous versions of a note are stored/
changes are logged (full audit trail)

Prevents deletion of notes by their author

Electronic signatures for completed
notes

Witnessing and freezing (makes note
immutable after the author and a witness
have signed it)
Direct link to laboratory equipment
(e.g. microscopes, spectrometers,
sequencers):

Automatic delivery of raw data by device

Delivery of metadata (e.g. date of last
calibration) from device
Annotation of attachments (e.g. images) * Extensions/API for customization
available
Analysis of raw data within the system
Search within the written text Assigning of tasks between colleagues * Data mining (aggregate and cluster
structured data)
Search in attachments * Inventory management:

Only amount and location of samples/
reagents
Notes can be shared with colleagues/
collaborators *

Abbreviations: API, Application programming interface; 21 CFR 11, code of federal regulations title 21 part 11; LIMS, Laboratory Information Management System. *Indicates that this feature is available in some systems of this category only.