Table 2.

Exposure rate (%) of drugs most prescribed of neonates admitted to NICUs in Brazil

GA < 28 weeks			GA 28–30 weeks			GA 31–33 weeks			GA 34–36 weeks			GA ≥ 37 weeks
	n	ER		n	ER		n	ER		n	ER		n	ER
aminophylline	22	3.99	aminophylline	29	3.52	aminophylline	36	5.10	gentamicin	28	3.97	fentanyl	23	2.77
phytomenadione	19	3.44	phytomenadione	28	3.40	ampicillin	27	3.82	ampicillin	26	3.69	heparin	23	2.77
multivitamins without mineralsa	18	3.26	multivitamins without mineralsa	27	3.28	gentamicin	27	3.82	fentanyl	21	2.98	gentamicin	18	2.17
folinic acid	17	3.08	heparin	25	3.03	dobutamine	19	2.69	multivitamins without mineralsa	20	2.84	ampicillin	17	2.05
ampicillin	16	2.90	folinic acid	24	2.91	phytomenadione	19	2.69	phytomenadione	19	2.70	metamizole	15	1.81
gentamicin	16	2.90	ampicillin	22	2.67	multivitaminsb	18	2.55	folinic acid	18	2.55	dobutamine	15	1.81
fentanyl	15	2.72	gentamicin	21	2.55	multivitamins without mineralsa	17	2.41	heparin	18	2.55	ranitidine	15	1.81
heparin	15	2.72	fentanyl	19	2.31	heparin	16	2.27	ranitidine	18	2.55	vancomycin	12	1.45
pulmonary surfactant	11	1.99	pulmonary surfactant	19	2.31	folinic acid	15	2.12	dobutamine	14	1.99	domperidone	11	1.33
meropenem	10	1.81	dobutamine	18	2.18	vancomycin	15	2.12	domperidone	13	1.84	alprostadil	10	1.20
vancomycin	10	1.81	domperidone	18	2.18	fentanyl	14	1.98	metamizole	12	1.70	phenobarbital	10	1.20
dobutamine	9	1.63	vancomycin	16	1.94	domperidone	11	1.56	multivitaminsb	11	1.56	phytomenadione	10	1.20
amphotericin B	6	1.09	meropenem	14	1.70	amikacin	10	1.42	pulmonary surfactant	9	1.28	folinic acid	9	1.08
cefepime	6	1.09	multivitaminsb	13	1.58	pulmonary surfactant	10	1.42	epinephrine	8	1.13	amikacin	9	1.08
domperidone	6	1.09	amikacin	8	0.97	ranitidine	8	1.13	furosemide	8	1.13	midazolam	9	1.08
teicoplanin	6	1.09	amphotericin B	8	0.97	cefepime	7	0.99	vancomycin	8	1.13	multivitamins without mineralsa	9	1.08
epinephrine	5	0.91	cefepime	8	0.97	metamizole	6	0.85	aminophylline	7	0.99	furosemide	8	0.96
tricalcium phosphate	5	0.91	epinephrine	8	0.97	hydrocortisone	6	0.85	cefepime	7	0.99	epinephrine	6	0.72
multivitaminsb	5	0.91	omeprazole	8	0.97	omeprazole	6	0.85	omeprazole	7	0.99	meropenem	6	0.72
ranitidine	5	0.91	tricalcium phosphate	7	0.85	epinephrine	5	0.71	amikacin	6	0.85	multivitaminsb	6	0.72
ferrous sulfate	5	0.91	ranitidine	7	0.85	tricalcium phosphate	5	0.71	mineral oil	6	0.85	dexamethasone	5	0.68

ER exposure rate per 100 neonates

^avitamins A, B₂, B₃, B₅, B₆, C, D, E

^bvitamins A, B₁, B₂, B₃, B₅, B₆, B₈, C, D₂, E