Table 1.
Relationship between NRP-1 protein expression and clinical pathological parameters
| Number | Lower level of NRP-1 | Higher level of NRP-1 | P value | |
|---|---|---|---|---|
| Gender | 0.738 | |||
| Male | 87 | 47 | 40 | |
| Female | 54 | 25 | 29 | |
| Age median (range):53.4 (27–82) | 0.345 | |||
| <60 | 93 | 43 | 50 | |
| ≥60 | 48 | 29 | 19 | |
| TNM stage | 0.019 | |||
| Stage 0 | 5 | 4 | 1 | |
| Stage I | 26 | 20 | 6 | |
| Stage II | 38 | 23 | 15 | |
| Stage III | 49 | 18 | 31 | |
| Stage IV | 23 | 7 | 16 | |
| WHO histologic classification | 0.046 | |||
| Tubular | 67 | 38 | 29 | |
| Papillary | 42 | 22 | 20 | |
| Mucinous | 13 | 4 | 9 | |
| Poorly cohesive | 11 | 3 | 8 | |
| Uncommon histologic variants | 8 | 5 | 3 | |
| Differentiation | 0.025 | |||
| Well | 35 | 27 | 8 | |
| Moderate | 74 | 36 | 38 | |
| Poor | 32 | 9 | 23 |
Notes: NRP-1, Neuropilin-1. P value was estimated by Mann Whitney test