Table II.
Frequencies of CD4+ T cells, CD8+ NK cells, and B cells that express α4β7hi in the PBMCs of Asian and African NHPs
| Species of Monkey/Chimp | n | % CD4 | % CD4+ α4β7hi | % CD8+ α4β7hi | % NK α4β7hi | % CD20+ α4β7hi |
|---|---|---|---|---|---|---|
| RM | 12 | 44.5 ± 12.3 | 11.6 ± 4.9* | 35.8 ± 7.9 | 32.9 ± 7.2 | 11.68 ± 4.9 |
| Pig-tailed | 6 | 28.6 ± 7.7 | 35.4 ± 7.2* | 11.9 ± 3.4 | 5.2 ± 1.8 | 6.9 ± 1.4 |
| SM | 12 | 22.3 ± 6.1 | 4.6 ± 2.5* | 7.7 ± 1.7 | 9.4 ± 3.5 | 4.2 ± 1.0 |
| Infant RM | 10 | 34.44 ± 9.2 | 12.6 ± 4.1 | 16.1 ± 6.4 | ND | 7.1 ± 4.2 |
| Infant SM | 4 | 55.15 ± 15.9 | 5.1 ± 1.6 | 4.31 ± 1.4 | 1.45 ± 0.73 | 0.85 ± 0.5 |
| African Green | 6 | 14.9 ± 7.4 | 5.2 ± 1.5 | 12.6 ± 4.2 | 18.6 ± 7.3 | 11.4 ± 4.7 |
| Baboons | 5 | 42.5 ± 8.1 | 12.2 ± 6.1 | 2.9 ± 1.8 | 5.6 ± 4.2 | 8.9 ± 2.9 |
| Blue sykes | 3 | 18.2 ± 4.3 | 11.7 ± 4.4 | 7.2 ± 1.8 | 5.8 ± 1.4 | 4.8 ± 1.1 |
| Chimpanzee | 6 | 45.6 ± 6.1 | 2.9 ± 0.8 | 2.8 ± 1.1 | 3.3 ± 1.1 | 4.9 ± 2.3 |
| Drill | 3 | 13.4 ± 3.2 | 15.6 ± 4.7 | 3.7 ± 1.1 | 4.2 ± 1.7 | 5.6 ± 2.2 |
| Gray mangabey | 3 | 26.1 ± 1.0 | 9.6 ± 3.4 | 8.1 ± 2.4 | 6.3 ± 2.9 | 5.3 ± 1.4 |
| Stump tailed | 6 | 33.1 ± 6.5 | 10.9 ± 5.7 | 4.9 ± 2.1 | 4.8 ± 3.1 | 1.9 ± 0.4 |
| Sykes | 3 | 26.4 ± 1.7 | 7.9 ± 3.4 | 4.2 ± 1.8 | 5.6 ± 4.2 | 7.8 ± 1.9 |
Numbers in bold highlight the major differences.
*
p < 0.0001, differences between PM and SM; p < 0.001, differences between PM and RM.