Table 1. Physiological roles and relating channelopathies of KCNQ subunits.

		Gene
		KCNQ1	KCNQ2	KCNQ3	KCNQ4	KCNQ5
Currents		Iks	M current	OHC, Iks	M current	M current
Expression location		Heart, cochlea	Brain, ganglia	Brain, ganglia	Cochlear	Brain, muscle
Sensory system	Olfactory		M current sensitive
	Vision	√			√	√
	Hearing	√			√
	Sensation		√	√		√
Neural circuits and disease	Pain		√	√	√	√
	BNFC		√	√
	LQT1	√
	DFNC2				√
	Memory		√	√	√
	Psychotic		√	?	√

BFNC, benign familial neonatal convulsions; LQT, long QT-syndrome; DFNA2, dominant progressive hearing loss; OHC, outer hair cell.