Table 1.
Levels of HMGB1 and PAI-1 before and after aHSCT
| Time of measurementa | HMGB1
|
PAI-1
|
||
|---|---|---|---|---|
| Level (ng/mL) | P-value | Level (ng/mL) | P-value | |
| Day −7 | 7.6±2.2 | – | 15.3±5.5 | – |
| Day 0 | 12.2±2.6 | <0.001 | 16.7±6.1 | NS |
| Day 4 | 10.3±3.1 | <0.01 | 16.9±6.3 | NS |
| Day 7 | 8.7±2.2 | NS | 17.4±5.8 | NS |
| Day 14 | 7.4±2.3 | NS | 18.2±7.5 | <0.05 |
| Day 21 | 7.0±2.1 | NS | 19.5±7.3 | <0.01 |
| Day 28 | 6.6±2.5 | NS | 21.7±7.7 | <0.01 |
Notes: Data are shown as the mean ± SD. Values are compared with those from day 7.
a
Time of measurement is shown before and after aHSCT. –, indicates no entry.
Abbreviations: NS, not significant; HMGB1, high-mobility group box 1; PAI-1, plasminogen activator inhibitor-1; aHSCT, allogeneic hematopoietic stem cell transplantation; SD, standard deviation.