Table 3. Relationships between total and subscale scores, age group and genotype.
| Factor | Total score (N = 166) | Sitting score (N = 223) | Standing and Walking score (N = 176) | Challenge score (N = 191) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Coefficienta (95%CI) | P value | n | Coefficienta (95%CI) | P value | N | Coefficienta (95%CI) | P value | n | ORb (95%CI) | P value | |
| Age group | ||||||||||||
| < 8 years | 35 | baseline | - | 40 | baseline | - | 36 | baseline | - | 39 | baseline | - |
| 8 < 13 years | 31 | -2 (-14,10) | 0.747 | 38 | -1 (-4,2) | 0.507 | 35 | -2 (-11,7) | 0.646 | 40 | 0.64 (0.23,1.74) | 0.381 |
| 13 < 19 years | 39 | -4 (-15,7) | 0.486 | 44 | -3 (-6,0) | 0.038 | 43 | -2 (-10,6) | 0.625 | 42 | 0.55 (0.20,1.51) | 0.248 |
| ≥ 19 years | 61 | -8 (-18,2) | 0.120 | 68 | -3 (-6,0) | 0.021 | 62 | -3 (-10,4) | 0.419 | 70 | 0.25 (0.10,0.65) | 0.004 |
| Mutation | ||||||||||||
| Large deletion | 13 | baseline | - | 14 | baseline | - | 15 | baseline | - | 14 | baseline | - |
| C-terminal deletion | 18 | 10 (-7,27) | 0.247 | 21 | 4 (0,8) | 0.068 | 18 | 9 (-3,21) | 0.139 | 18 | 1.85 (0.36,9.60) | 0.462 |
| Early truncating | 13 | 1 (-17,19) | 0.915 | 14 | 1 (-4,6) | 0.678 | 13 | 0 (-13,13) | 1.000 | 14 | 0.56 (0.08,4.18) | 0.573 |
| p.Arg106Trp | 10 | 11 (-9,31) | 0.278 | 10 | 2 (-3,7) | 0.453 | 11 | 0 (-14,14) | 1.000 | 12 | 1.70 (0.27,10.73) | 0.575 |
| p.Arg133Cys | 13 | 21 (3,39) | 0.025 | 13 | 4 (-1,9) | 0.102 | 14 | 19 (6,32) | 0.003 | 16 | 3.34 (0.64,17.33) | 0.151 |
| p.Arg168* | 17 | 11 (-6,28) | 0.212 | 20 | 4 (0,8) | 0.073 | 18 | 7 (-5,19) | 0.251 | 21 | 0.75 (0.13,4.20) | 0.743 |
| p.Arg255* | 11 | -1 (-20,18) | 0.918 | 15 | -1 (-6,4) | 0.673 | 11 | 0 (-14,14) | 1.000 | 15 | 0.99 (0.16,6.24) | 0.992 |
| p.Arg270* | 16 | 0 (-18,18) | 1.000 | 18 | -1 (-5,3) | 0.661 | 17 | 2 (-10,14) | 0.748 | 17 | 1.09 (0.19,6.34) | 0.924 |
| p.Arg294* | 11 | 24 (5,43) | 0.015 | 17 | 4 (-1,9) | 0.084 | 12 | 15 (2,28) | 0.027 | 15 | 4.38 (0.82,23.37) | 0.084 |
| p.Arg306Cys | 10 | 23 (3,43) | 0.022 | 11 | 5 (0,10) | 0.051 | 10 | 21 (7,35) | 0.003 | 11 | 2.13 (0.35,12.93) | 0.412 |
| p.Thr158Met | 14 | 5 (-13,23) | 0.590 | 15 | 1 (-4,6) | 0.677 | 15 | 3 (-10,16) | 0.640 | 15 | 0.78 (0.12,5.03) | 0.797 |
| Other | 20 | 13 (-4,30) | 0.135 | 22 | 4 (0,8) | 0.072 | 22 | 6 (-6,18) | 0.313 | 23 | 2.31 (0.46,11.50) | 0.308 |
a Coefficient values represent change in the outcome in relation to the predictor relative to the median value of the baseline group.
b Odds ratio refers to the odds of the outcome given exposure to the predictor variable.