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. 2016 Jan 22;11(1):e0147173. doi: 10.1371/journal.pone.0147173

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© 2016 Shen et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — A, RGD-fiber modified infection capacity of adenoviruses. Western blot analysis of hexon protein expression in mock infection (1) or infection with AxCAlacZ (2) and AxCAZ3-F/RGD (3) in prostate cancer cells. B, Flow cytometric analysis of hexon protein expression in AxCAZ3-F/RGD adenovirus-infected cells or AxCAlacZ adenovirus-infected cells. Data are presented as means ± standard deviation for three independent experiments. **P < 0.01 and N.S., not statistically significant. C, Cytopathic effects of RGD-fiber modified adenoviruses on prostate cancer cells. Cells were infected with AxCAlacZ (diamonds), AxCAZ3-F/RGD (squares), AxdAdB-3 (triangles) and AxdAdB3-F/RGD (circles) at a MOI of 30 for 0, 1, 3, 5, and 7 days and then subjected to a cell viability assay. Data are presented as means ± standard deviation for three independent experiments. **P < 0.01 and N.S., not statistically significant.