Table 1. Terms introduced to simulate different dialysis timeframes using our calibrated kinetic models.
| Strategy | TT/week(h) | BV/week(L) | QB(mL/min) | QD(mL/min) | QUF | ER(%) |
|---|---|---|---|---|---|---|
| 3x4h_300/w | 12 | 216 | 300 | 700 | a.m.* | a.m.* |
| 3x8h_150/w | 24 | 216 | 150 | 700 | a.m.*/2 | a.m.* x 1.33 (urea) [40] |
| a.m.* x 1.00 (PBS) [41] | ||||||
| 6x2h_300/w | 12 | 216 | 300 | 700 | a.m.* | a.m.* |
| 6x4h_150/w | 24 | 216 | 150 | 700 | a.m.*/2 | a.m.* x 1.33 (urea) [40] |
| a.m.* x 1.00 (PBS) [41] | ||||||
| 3x8h_300/w | 24 | 432 | 300 | 700 | a.m.*/2 | a.m.* |
| 6x4h_300/w | 24 | 432 | 300 | 700 | a.m.*/2 | a.m.* |
| 6x8h_150/w | 48 | 432 | 150 | 700 | a.m.*/4 | a.m.* x 1.33 (urea) [40] |
| a.m.* x 1.00 (PBS) [41] |
3x4h_300/w: thrice weekly 4 h dialysis with QB300; 3x8h_150/w: thrice weekly extended (8 h) dialysis with QB150; 6x2h_300/w: frequent (6 times) short (2h) dialysis with blood flow QB300; 6x4h_150/w: frequent 4 h dialysis with QB150; 3x8h_300/w thrice weekly extended dialysis with QB300; 6x4h_300/w: frequent 4 h dialysis with QB300; 6x8h_150/w: frequent extended dialysis with QB150. TT: treatment time; BV: processed blood volume; ER: extraction ratio; PBS: protein-bound solutes
a.m.*: as measured in the present kinetic study during 4 h dialysis