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. 2016 Jan 22;11(1):e0147159. doi: 10.1371/journal.pone.0147159

Table 3. Kinetically derived parameters for the various solutes as derived from measured solute concentrations during a single midweek dialysis session.

Solute V1(L) Vtot(L) K21(mL/min)
urea 10.2 ± 5.6 32.9 ± 8.1 457 ± 175
PCG 8.2 ± 2.4 18.9 [15.7;25.2] 103 ± 47 α
HA 8.4 ± 3.8 20.9 ± 4.7 α 169 ± 81 α
IAA 4.9 ± 1.5 αβ 24.7 ± 10.6 123 ± 46 α
IS 3.7 [3.7;4.2] αβ 16.5 ± 6.5 α 85 ± 72 α
PCS 3.8 ± 0.9βγ 10.4 [9.8;15.1] αδ 87 ± 44 α

V1: plasmatic volume, Vtot: total distribution volume, K21: intercompartment clearance. PCG: p-cresylglucuronide, HA: hippuric acid, IAA: indole acetic acid, IS: indoxyl sulfate, PCS: p-cresylsulfate. P<0.05:

αversus urea;

βversus PCG;

γversus HA;

δversus IAA.