Table 1.

Characteristics of studies reporting the distribution of three APOC3 polymorphisms (SstI,-455T/C,-482C/T) in CHD cases and controls

Study [Reference]	Year	Eligible subjects		Allele frequency (case)			Method	Population	Criteria	Gender (male), %		Age (years)
		case	control	S2	T	C				Case	Control	Case	Control
Aalto-Setälä [12]	1987	39	61	0.115	-	-	PCR-RFLP	Finnish	CHD	100	50.8	38-68	18-52
Bai [13]	1995	90	68	0.328	-	-	PCR-RFLP	Japanese	CHD	77.8	57.4	63±12	58±12
Berkinbayev [14]a	2014	161	112	0.242	-	-	PCR	Kazakhstan(Kazakh)	MI	100	100	46.4±1.9	40.7±2.1
Berkinbayev [14]b	2014	80	95	0.285	-	-	PCR	Kazakhstan(Uyghur)	CHD	100	100	47.3±0.92	41.2±1.02
Bi [15]	2005	312	317	-	-	0.452	PCR-RFLP	Chinese(Han)	CAD	67	60.3	60.2±13.3	58.9±14.3
Che [16]	2012	78	78	-	-	0.647	PCR-RFLP	Chinese	CAD	57.7	52.6	45.3±4.7	44.3±7.6
Chen [17]	2006	310	499	-	0.477	0.455	PCR-RFLP	Chinese(Han)	CHD	70.6	62.7	60.56±11.14	58.87±9.11
Chhabra [18]	2004	158	151	0.342	-	-	PCR	India	CAD	88	92	53.25±10.25	52.45±10.85
Dallongeville [19]	2006	442	475	-	-	0.263	PCR	French	CHD	100	100	35-64	35-64
Dan [20]	1995	43	60	0.221	-	-	PCR-RFLP	Chinese	CHD	N/A	N/A	57.6-6.9	55.4-4.3
Ding [21]	2012	229	254	-	0.548	-	PCR	Chinese(Han)	ACS	55.9	53.9	59.1±9.4	59.3±9.6
Han [22]	2011	275	289	-	-	0.481	PCR-RFLP	Chinese(Han)	CHD	56.4	56.4	59.2±9.8	61.6±10.7
Izar [23]	2003	112	112	0.136	-	-	PCR	Brazil	CAD	58	59	M<45, W<55	N/A
Kee [24]	1999	614	761	0.093	-	-	PCR	Europe	MI	100	100	25-64	N/A
Li [25]	2006	47	104	0.274	-	-	PCR-RFLP	Chinese(Han)	CAD, MI	72.3	60.6	62.5±12.1	60.0±8.0
Liu [26]	2004	385	373	0.116	-	-	PCR-RFLP	Caucasian	MI	100	100	60±9	59±9
Liu [27]	2005	483	502	0.301	0.534	0.449	PCR-RFLP	Chinese(Han)	CHD	59	63.1	54.2±6.3	58.2±6.2
Liu [28]	2005	267	491	0.301	-	-	PCR-RFLP	Chinese(Han)	CHD	70.4	63.7	60.3±8.9	58.8±9.2
Martinelli [29]	2007	669	244	-	-	-	PCR	Italy	CAD, MI	81.3	75	60.7±9.3	58.7±12.7
Muendlein [30]	2008	332	225	-	-	0.297	PCR	Caucasian	CAD	79.5	54.7	62.5±10.3	61.5±10.2
Olivieri [31]	2002	549	251	-	0.416	-	PCR	Northern Italy	CAD	81.8	66.9	60.4±9.4	57.6±12.6
Ordovas [32]	1991	202	145	0.125	-	-	PCR-RFLP	Northern Italy	CAD	N/A	N/A	47.2±8.8	49.6±6.9
Paulweber [33]	1988	106	118	0.104	-	-	PCR-RFLP	Austrian	CAD, MI	100	100	47.3±5.7	49.7±5.4
Rigoli [34]	1995	62	62	0.169	-	-	PCR-RFLP	Southern Italy	CHD	69.4	67.7	58.2±7.1	57.6±7.7
Sediri [35]	2011	326	361	0.103	0.411	-	PCR	Tunisia	MI	100	100	53.8±8.6	51.1±9.5
Tarek [36]	2013	156	154	0.292	-	-	PCR-RFLP	Egyptian	CAD	100	100	51.5±7.9	50.7±9.4
Tarek [37]	2011	200	100	0.145	-	-	PCR	Egyptian	MI	67	64	50.7±9.5	52.9±11.3
Tobin [38]	2004	547	505	-	0.355	0.255	PCR-RFLP	UK	MI	68	62	61.9±9.2	58.6±10.7
Weng [39]	2000	50	50	0.16	-	-	PCR	Chinese(Han)	CAD, MI	76	74	57±6.8	55±8.7
Wu [40]	2000	131	229	0.233	-	-	PCR	Chinese	CAD	69.5	56.8	59.1±10.9	51±15.3
Yang [41]	2008	85	87	-	-	0.412	PCR-RFLP	Chinese	CHD	54.1	52.9	52.79±7.15	50.63±7.50
Yi [42]	2006	195	181	-	-	0.541	PCR-RFLP	Chinese (Han)	CAD	56.4	56.4	69.48±9.21	58.63±14.79
Yu [43]	2011	286	325	-	0.42	0.517	TaqMan	Chinese (Han)	CHD	74.8	52.9	56.30±11.57	55.79±12.40