Table 1. Parameters for BLASTp.

	a	b	c	d
Program	BLAST+ 2.2.28	BLASTp of DEG 10	BLAST+ 2.2.28	BLAST+ 2.2.28
Query name	COPs	Non-homologous COPs	Non-homologous COPs	Hypothetical proteins
No. of queries	241	198	198	114
Subject name	Human proteome	DEG	VFDB	PDB proteins
No. of subjects	68,939	12,379	2,447	252,484
E-value	1.00E-03	1.00E-05	1.00E-04	1.00E-05