Table 6. S. enterica eight genes as drug targets–data from DrugBank.
Genes | Molecule | Output | Reason |
---|---|---|---|
16S rRNA | Nucleic Acid | excluded | Not the aim |
30S ribosomal protein S10 | Protein | X | Not in UMPs of SE |
30S ribosomal protein S12 | Protein | X | Not in UMPs of SE |
DNA gyrase subunit A | Enzyme | X | Not in UMPs of SE |
DNA topoisomerase 4 subunit A | Enzyme | X | Not in UMPs of SE |
Oxygen-insensitive NADPH nitroreductase | Enzyme | X | In 35/42 strains |
Penicillin-binding protein 2 | Enzyme | present | Included |
Probable pyruvate-flavodoxin oxidoreductase | Enzyme | X | Not in UMPs of SE |