Table 2.

Response rates of commonly used first line and second line systemic therapy

Organ/Systemic treatment	Response rate of 1st line treatment	Response rate of 2nd line treatment
Breast Chemotherapy	42%–72% [[35], [36], [37], [38]] (Docetaxel) 73% (FAC) [39]	42% (retry Docetaxel) [40] 30% (Gemcitabine/Vinorelbine) [41] 30% (Capecitabine) [42]
Breast Hormone	30% (Letrozole) 20% (Tamoxifen) [43]	30.7% (Exemestane+GnRH agonist in pre-menopausal women) [44] 14.3% (Fulvestrant) [45]
Lung Chemotherapy	30.6% (Pemetrexed/Cisplatin) 28.2% (Gemcitabine/cisplatin) [46]	12% (Docetaxel) [47]
Colorectal Chemotherapy+Targeted therapy	64% (Oxaliplatin+Cetuximab) [48]	10.8% (FOLFIRI) 22.9% (FOLIFIRI+Cetuximab) [49]