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. 2013 Jun 7;2(3):110–115. doi: 10.1016/j.jbo.2013.05.003

Fig. 2.

Fig. 2

Zoledronic acid and atorvastatin increase VEGF expression in breast cancer cell lines. (A+B) Treatment with zoledronic acid (100 µM) or atorvastatin (10 µM) for 6, 24, and 48 h results in a time-dependent increase of VEGF expression in MDA-231 cells. Data are presented as the percentage expression relative to control treated (PBS, DMSO) cells, and are mean±SD of 3 independent experiments. (C) Treatment of MDA-231 cells with zoledronic acid (100 µM) for 24 h increases VEGF protein in the cell supernatant. Values are mean±SD of 3 independent experiments. **P<0.01.