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Effect of OPG gene transfer on bone lesions associated with EWS progression in mice. (A) Tumor-associated osteolysis was analyzed by microCT at day 42 on 3 representative pcDNA3.1 mice and hOPG mice. The relative bone volume (BV/TV) is expressed as percent in each case. (B) Tumor-associated osteolysis analyzed by radiography at day 42 on pcDNA3.1 mice and hOPG mice.
