Table 2.
Histochemical staining of mucins in gastric biopsy specimens
Antigen | H.pylori negative | H.pylori positive | |
MUC5AC | % Stained*a, intensity score (surface) | (69.8% ± 3.5%), 2.8 ± 0.1 | (51.2% ± 5.7%), 2.6 ± 0.1 |
MUC6 | % Stained**a, intensity score (surface)a | 4%, 0.1 ± 0.1 | 72%, 1.8 ± 0.2 |
Le\ + b | % Stained**a, intensity score (surface)a | 63%, 0.9 ± 0.2 | 96%, 1.9 ± 0.2 |
Paradoxical ConA | % Stained**a, intensity score (surface)a | 18%, 0.4 ± 0.2 | 79%, 2.1 ± 0.3 |
LeX | % Stained**a, intensity score (surface)a | 4%, 0.4 ± 0.4 | 59%, 1.0 ± 0.2 |
MUC1 | Intensity score (surface), intensity score(glands) | 2.6 ± 0.2, 1.7 ± 0.1 | 2.7 ± 0.1, 1.4 ± 0.2 |
Sialyl Tn | Intensity score (surface), intensity score (glands)a | 1.8 ± 0.2, 1.9 ± 0.1 | 1.6 ± 0.1, 1.4 ± 0.1 |
% of surface epithelium stained; **% of patients with surface staining;
P < 0.05, H.pylori positive vs H.pylori negative