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Effect of KLF15 on activation of the ERK1/2 MAPK pathway in MCs. A. MCs transfected with empty vector or KLF15 OE and incubated with 25 mM glucose (HG) for 24 h, and the ERK1/2 phosphorylation was determined using phospho-ERK1/2 specific antibody. B. The ratio of p-ERK1/2/ ERK1/2. Data represent means ± SD. of three experiments. *P < 0.05 vs. NG group, #P < 0.05 vs. HG group. NG, normal glucose; OE, overexpression.
