Table 2.

Results of meta-analysis for PTGS2 rs20417 polymorphism and PCa risk

Study groups	Comparisons	Main effects of rs20417 polymorphism on PCa risk			Analysis model	Total (case/control)
		OR (95% CI)	Ph	I2 (%)
All	10					12326/14027
CC vs. GG	9	1.00 (0.87, 1.15)	0.962	0	Fixed
CC + GC vs. GG	10	1.01 (0.96, 1.06)	0.585	0	Fixed
CC vs. GC + GG	9	0.99 (0.86, 1.14)	0.952	0	Fixed
C vs. G	10	1.01 (0.96, 1.06)	0.542	0	Fixed
GC vs. GG	10	1.01 (0.96, 1.07)	0.528	0	Fixed
Ethnicity						359/359
African	2
CC vs. GG	2	0.93 (0.44, 1.95)	0.616	0	Fixed
CC + GC vs. GG	2	0.95 (0.66, 1.35)	0.721	0	Fixed
CC vs. GC + GG	2	0.89 (0.43, 1.82)	0.528	0	Fixed
C vs. G	2	0.94 (0.69, 1.29)	0.919	0	Fixed
GC vs. GG		0.94 (0.64, 1.39)	0.564	0	Fixed
Caucasian	6					11554/12982
CC vs. GG	5	1.01 (0.87, 1.17)	0.821	0	Fixed
CC + GC vs. GG	6	1.02 (0.96, 1.07)	0.854	0	Fixed
CC vs. GC + GG	5	1.00 (0.87, 1.16)	0.848	0	Fixed
C vs. G	6	1.01 (0.97, 1.06)	0.789	0	Fixed
GC vs. GG	6	1.02 (0.96, 1.07)	0.858	0	Fixed
Asian	2					413/686
CC vs. GG	1	0.85 (0.34, 2.10)	.	.	Fixed
CC + GC vs. GG	2	0.88 (0.65, 1.19)	0.031	78.6	Fixed
CC vs. GC + GG	1	0.79 (0.32, 1.94)	.	.	Fixed
C vs. G	2	0.87 (0.66, 1.06)	0.033	77.9	Fixed
GC vs. GG	2	0.89 (0.64, 1.22)	0.023	80.7	Fixed
Source of controls
Population	7					11952/13599
CC vs. GG	6	1.01 (0.87, 1.17)	0.902	0	Fixed
CC + GC vs. GG	7	1.01 (0.96, 1.06)	0.424	0	Fixed
CC vs. GC + GG	6	1.01 (0.87, 1.16)	0.917	0	Fixed
C vs. G	7	1.01 (0.96, 1.06)	0.363	8.6	Fixed
GC vs. GG	7	1.01 (0.95, 1.06)	0.403	3.0	Fixed
Hospital	2					285/340
CC vs. GG	1	0.85 (0.34, 2.10)	.	.	Fixed
CC + GC vs. GG	2	1.19 (0.81, 1.75)	0.349	0	Fixed
CC vs. GC + GG	1	0.79 (0.32, 1.94)	.	.	Fixed
C vs. G	2	1.13 (0.80, 1.58)	0.331	0	Fixed
GC vs. GG	2	1.27 (0.84, 1.91)	0.369	0	Fixed