Table 3.
The genotype frequencies for Leu125Val in PECAM-1 between severe sepsis and septic shock patients
| Genotype | Severe sepsis (n = 95) | Septic shock (n = 122) | OR (95% CI) | P value |
|---|---|---|---|---|
|
| ||||
| n (%) | n (%) | |||
| Leu/Leu | 25 (26.3) | 14 (11.5) | 1 | |
| Leu/Val | 48 (50.5) | 67 (54.9) | 2.493 (1.175, 5.287) | 0.016 |
| Val/Val | 22 (23.2) | 41 (33.6) | 3.328 (1.445, 7.666) | 0.004 |
Note: Compared with the Leu/Leu genotype, the Leu/Val and Val/Val genotypes were significantly correlated with an increased risk of septic shock. OR = odds ratio; CI = confidence interval.