Table 3.
Subgroup analysis of outcomes depending on retrospective studies and retrospective match studies
| Comparison | Pooled estimates | 95% CI | P | I2 |
|---|---|---|---|---|
| Tumor margin | WMD 0.12 | 0.04-0.21 | 0.03 | 28% |
| Studies with RM | WMD 0.10 | 0.01-0.20 | 0.06 | 7% |
| Studies without RM | WMD 0.18 | 0.02-0.35 | 0.03 | 0% |
| Omit Truant et al. | WMD 0.19 | 0.05-0.33 | 0.01 | 0% |
| Operating time | WMD -10.36 | -26.21-5.49 | 0.20 | 36% |
| Studies with RM | WMD -15.95 | -52.86-20.96 | 0.40 | 60% |
| Studies without RM | WMD -8.06 | -23.80-7.69 | 0.32 | 17% |
| Omit Belli et al. | WMD -6.12 | -27.66-15.43 | 0.58 | 42% |
| Blood loss | WMD -157.25 | -295.05-19.45 | 0.03 | 84% |
| Studies with RM | WMD -41.11 | -151.95-69.74 | 0.47 | 0% |
| Studies without RM | WMD -250.12 | -420.36-79.89 | 0.004 | 85% |
| Omit Belli et al. | WMD -121.63 | -308.77-65.50 | 0.20 | 83% |
| Blood transfusion | RR 0.41 | 0.22-0.74 | 0.004 | 40% |
| Studies with RM | RR 0.47 | 0.08-2.86 | 0.41 | 0% |
| Studies without RM | RR 0.45 | 0.10-1.98 | 0.29 | 63% |
| Omit Belli et al. | RR 0.38 | 0.16-0.93 | 0.20 | 83% |
| Postoperative morbility | RR 0.48 | 0.35-0.66 | < 0.001 | 40% |
| Studies with RM | RR 0.52 | 0.33-0.81 | 0.004 | 0% |
| Studies without RM | RR 0.45 | 0.17-1.16 | 0.10 | 71% |
| Omit Belli et al. | RR 0.48 | 0.26-0.86 | 0.01 | 52% |
| Death | RR 0.72 | 0.28-1.81 | 0.48 | 19% |
| Studies with RM | RR 1.10 | 0.35-3.49 | 0.87 | 47% |
| Studies without RM | RR 0.36 | 0.07-1.98 | 0.24 | 0% |
| Omit Truant et al. | RR 0.96 | 0.34-2.70 | 0.68 | 36% |
| Curative resection | RR 1.15 | 0.90-1.47 | 0.26 | 90% |
| Studies with RM | RR 1.13 | 0.98-1.30 | 0.08 | NA |
| Studies without RM | RR 1.17 | 0.72-1.91 | 0.52 | 95% |
| Omit Siniscalchi et al. | RR 1.25 | 0.99-1.58 | 0.06 | 75% |
| Length of hospital stay | WMD -4.11 | -6.23-1.98 | < 0.001 | 82% |
| Studies with RM | WMD -3.11 | -4.42-1.80 | < 0.001 | 0% |
| Studies without RM | WMD -5.23 | -9.70-0.76 | 0.02 | 88% |
| Omit Belli et al. | WMD -4.78 | -6.68-2.88 | < 0.001 | 50% |
Abbreviations: LH = laparoscopic hepatectomy; OH = open hepatectomy; RM = retrospective matching study; RR = risk ratio; WMD = weigh mean difference CI = confidence interval.