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. 2015 Nov 15;8(11):20690–20700.

Table 2.

Summary of different comparative results

No. of studies OR (95% CI) P I2 ph Model Publication bias

Egger Begg
-308G>A
    Dominant model (GG+GA vs. AA) 14 0.53 (0.35-0.81) 0.004 26.2% 0.17 Fix 0.83 0.66
    Recessive model (GG vs. GA+AA) 17 0.83 (0.62-1.10) 0.19 65.4% <0.001 Random 0.90 0.82
    Homozygote model (GG vs. AA) 14 0.51 (0.33-0.78) 0.002 35.6% 0.09 Fix 0.84 0.83
    Additive model (G vs. A) 17 0.81 (0.63-1.04) 0.11 68.0% <0.001 Random 0.43 0.77
-863C>A
    Dominant model (CC+CA vs. AA) 4 0.78 (0.25-2.47) 0.67 72.8% 0.01 Random 0.03 0.73
    Recessive model (CC vs. CA+AA) 4 1.01 (0.83-1.22) 0.96 0 0.72 Fix 0.06 0.31
    Homozygote model (CC vs. AA) 4 0.80 (0.25-2.53) 0.70 71.7% 0.01 Random 0.10 0.73
    Additive model (C vs. A) 4 1.08 (0.80-1.47) 0.61 61.0% 0.05 Random 0.88 0.73
-857C>T
    Dominant model (CC+CT vs. TT) 5 2.10 (0.77-5.75) 0.15 54.0% 0.07 Random 0.42 0.81
    Recessive model (CC vs. CT+TT) 5 0.84 (0.45-1.57) 0.59 85.0% <0.001 Random 0.24 0.46
    Homozygote model (CC vs. TT) 5 2.11 (0.72-6.12) 0.17 58.6% 0.047 Random 0.61 1.00
    Homozygote model (C vs. T) 5 0.92 (0.55-1.53) 0.73 84.5% <0.001 Random 0.13 0.46
-238G>A
    Dominant model (GG+GA vs. AA) 4 0.33 (0.18-0.57) <0.001 19.9% 0.29 Fix 0.33 0.09
    Recessive model (GG vs. GA+AA) 8 0.62 (0.30-1.30) 0.21 85.4% <0.001 Random 0.59 0.71
    Homozygote model (GG vs. AA) 4 0.34 (0.06-2.12) 0.25 56.1% 0.078 Random 0.17 0.31
    Additive model (G vs. A) 8 0.67 (0.35-1.26) 0.21 85.4% <0.001 Random 0.32 0.39

Note. OR: Odds ratio; CI: Confidence interval; ph: P value of heterogeneity.