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. 2015 Nov 15;8(11):20690–20700.

Table 3.

Results of subgroup analysis

Polymorphisms No. of studies Dominant model Recessive model Homozygote model Additive model




OR (95% CI) p OR (95% CI) P OR (95% CI) P OR (95% CI) P
-308G>A Ethnicity
    Asian 12 0.76 (0.44-1.32) 0.33 0.82 (0.61-1.10) 0.18 0.71 (0.42-1.20) 0.20 0.86 (0.69-1.08) 0.20
    African 2 0.16 (0.06-0.39) <0.001 0.60 (0.24-1.54) 0.29 0.14 (0.06-0.36) <0.001 0.50 (0.24-1.08) 0.08
    Caucasian 3 0.83 (0.35-0.81) 0.75 1.10 (0.48-2.51) 0.83 1.17 (0.24-5.71) 0.84 0.81 (0.63-1.05) 0.97
HIV Status
    HIV negative 7 0.55 (0.25-1.21) 0.14 0.78 (0.51-1.18) 0.23 0.49 (0.22-1.08) 0.08 0.79 (0.55-1.14) 0.21
    HIV NA 7 0.52 (0.32-0.87) 0.012 0.88 (0.57-1.35) 0.55 0.52 (0.31-0.85) 0.01 0.83 (0.56-1.22) 0.33
-863C>A HIV Status
    HIV negative 1 - - - - - - - -
    HIV NA 3 0.43 (0.24-0.78) 0.005 0.98 (0.79-1.21) 0.83 0.44 (0.24-0.79) 0.006 1.12 (0.93-1.34) 0.24
-857C>T HIV Status
    HIV negative 1 - - - - - - - -
    HIV NA 4 2.61 (0.73-9.31) 0.14 0.85 (0.41-1.78) 0.66 2.65 (0.70-10.05) 0.85 0.91 (0.49-1.68) 0.76
-238G>A Ethnicity
    Asian 7 0.31 (0.18-0.56) <0.001 0.69 (0.28-1.71) 0.42 0.33 (0.03-3.27) 0.34 0.72 (0.31-1.68) 0.45
    Caucasian 1 - - - - - - - -
HIV Status
    HIV negative 2 - - 0.68 (0.23-2.02) 0.48 0.68 (0.06-2.12) 0.81 0.51 (0.33-0.81) 0.04
    HIV NA 6 0.32 (0.17-0.57) <0.001 0.48 (0.24-0.96) 0.04 0.33 (0.03-3.27) 0.34 0.72 (0. 27-1.92) 0.51