Table 3.
Polymorphisms | No. of studies | Dominant model | Recessive model | Homozygote model | Additive model | |||||
---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||||
OR (95% CI) | p | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |||
-308G>A | Ethnicity | |||||||||
Asian | 12 | 0.76 (0.44-1.32) | 0.33 | 0.82 (0.61-1.10) | 0.18 | 0.71 (0.42-1.20) | 0.20 | 0.86 (0.69-1.08) | 0.20 | |
African | 2 | 0.16 (0.06-0.39) | <0.001 | 0.60 (0.24-1.54) | 0.29 | 0.14 (0.06-0.36) | <0.001 | 0.50 (0.24-1.08) | 0.08 | |
Caucasian | 3 | 0.83 (0.35-0.81) | 0.75 | 1.10 (0.48-2.51) | 0.83 | 1.17 (0.24-5.71) | 0.84 | 0.81 (0.63-1.05) | 0.97 | |
HIV Status | ||||||||||
HIV negative | 7 | 0.55 (0.25-1.21) | 0.14 | 0.78 (0.51-1.18) | 0.23 | 0.49 (0.22-1.08) | 0.08 | 0.79 (0.55-1.14) | 0.21 | |
HIV NA | 7 | 0.52 (0.32-0.87) | 0.012 | 0.88 (0.57-1.35) | 0.55 | 0.52 (0.31-0.85) | 0.01 | 0.83 (0.56-1.22) | 0.33 | |
-863C>A | HIV Status | |||||||||
HIV negative | 1 | - | - | - | - | - | - | - | - | |
HIV NA | 3 | 0.43 (0.24-0.78) | 0.005 | 0.98 (0.79-1.21) | 0.83 | 0.44 (0.24-0.79) | 0.006 | 1.12 (0.93-1.34) | 0.24 | |
-857C>T | HIV Status | |||||||||
HIV negative | 1 | - | - | - | - | - | - | - | - | |
HIV NA | 4 | 2.61 (0.73-9.31) | 0.14 | 0.85 (0.41-1.78) | 0.66 | 2.65 (0.70-10.05) | 0.85 | 0.91 (0.49-1.68) | 0.76 | |
-238G>A | Ethnicity | |||||||||
Asian | 7 | 0.31 (0.18-0.56) | <0.001 | 0.69 (0.28-1.71) | 0.42 | 0.33 (0.03-3.27) | 0.34 | 0.72 (0.31-1.68) | 0.45 | |
Caucasian | 1 | - | - | - | - | - | - | - | - | |
HIV Status | ||||||||||
HIV negative | 2 | - | - | 0.68 (0.23-2.02) | 0.48 | 0.68 (0.06-2.12) | 0.81 | 0.51 (0.33-0.81) | 0.04 | |
HIV NA | 6 | 0.32 (0.17-0.57) | <0.001 | 0.48 (0.24-0.96) | 0.04 | 0.33 (0.03-3.27) | 0.34 | 0.72 (0. 27-1.92) | 0.51 |