Table 2.

Frequency distribution of CYP2C9 polymorphisms in 100 Li subjects

SNP	Region	Position	Nucleotide change	Amino-acid effect	Frequency % (n)
rs148342296	Promoter	-477	A > G	No translateda	11/99
rs9332105	Intron 1	486	G > C	No translated	52/98
rs201856860	Exon 3	3514	T > C	Ile112 = silentb	1/100
rs12414460	Exon 3	3549	G > A	Arg124Glnmissensec	2/100
rs9332127	Intron 3	9032	G > C	No translated	3/99
rs9332172	Intron 5	33349	A > G	No translated	5/100
rs148303924	Intron 5	33622	T > C	No translated	1/100
rs1057910	Exon 7	42614	A > C	Ile359Leumissensec	2/99
rs17847029	Intron 7	42726	C > T	No translated	7/99
rs93321230	Intron 8	47545	A > T	No translated	2/100
rs2298037	Intron 8	47639	C > T	No translated	54/100
rs147375734	Intron 8	47947	T > C	No translated	3/98
rs28371688	Intron 8	50053	G > A	No translated	2/100
rs1934669	Intron 8	50056	A > T	No translated	56/100
rs1057911	Exon 9	50298	A > T	Gly475 = silentb	2/100
rs9332244	3’-UTR	50566	A > G	No translated	9/100
rs9332245	3’-UTR	50742	T > A	No translated	2/100

SNP, single nucleotide polymorphism;

^aNon translated: These synonymous SNP mutations have no effect on protein sequence;

^bsilent mutation;

^cmissense mutation.