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. 2015 Nov 15;8(11):21024–21033.

Table 4.

Three types of CYP2C9 allele frequencies in different populations

Races N CYP2C9*1 p CYP2C9*2 p CYP2C9*3 p Ref
Li 100 0.98 / 0 / 0.01 / Current study
East Asians
    Tibetan Chinese 96 0.938 0.259 0 / 0.057 0.150 [13]
    Tibetan Chinese 107 0.972 0.938 0 / 0.028 0.664 [19]
    Han Chineese 2127 0.945 0.128 0.001 / 0.029 0.416 [16]
    Korean 358 0.934 0.077 0 / 0.06 0.074 [20]
    Korean 574 0.98 0.69 0 / 0.011 0.664 [21]
    Japanese 218 0.979 0.714 0 / 0.021 0.815 [22]
    Uyghur Chinese 214 0.902 0.013* 0.096 0.001* 0 0.318 [23]
    Bai Chinese 132 0.955 0.501 0 / 0.045 0.246 [19]
    Hui Chinese 164 0.954 0.448 0.046 0.073 0 0.379 [23]
    Mongolian Chinese 560 0.97 0.820 0 / 0.03 0.422 [24]
    Vietnamese 157 0.978 0.737 0 / 0.022 0.819 [25]
    Malay 209 0.957 0.488 0.019 0.397 0.024 0.694 [26]
    Tamil Nadu 135 0.907 0.022* 0.026 0.280 0.067 0.070 [27]
Middle East Arab
    Saudi (Al-Ahsa) 131 0.844 < 0.001* 0.13 < 0.001* 0.023 0.809 [28]
    Saudi (Riyadh) 192 0.792 < 0.001* 0.117 < 0.001* 0.091 0.007* [29]
    Egyptian 247 0.820 < 0.001* 0.12 < 0.001* 0.06 0.082 [30]
    Jordanian 263 0.797 < 0.001* 0.135 < 0.001* 0.068 0.026* [31]
    Lebanese 161 0.792 < 0.001* 0.112 < 0.001* 0.096 0.005* [32]
    Omani 189 0.897 0.01* 0.074 0.012* 0.029 0.535 [33]
Africans
    Ethiopian 150 0.934 0.171 0.043 0.090 0.023 0.785 [34]
    African-American 600 0.867 0.001* 0.028 0.180 0.02 0.775 [35]
    African-American 490 / / 0.011 1 0.018 0.888 [36]
    Beninese 111 0.955 0.530 0 / 0 0.474 [37]
    Ghanaian 204 / / 0 / 0 0.329 [6]
    Iranian 200 / / 0.13 < 0.001* 0 0.333 [38]
Caucasians
    Turkish 499 0.794 < 0.001* 0.106 < 0.001* 0.1 0.003* [39]
    Brazilian 103 0.83 < 0.001* 0.097 0.004* 0.073 0.059 [40]
    Mexican 98 0.86 0.002* 0.08 0.012* 0.06 0.125 [41]
    Ecuadorian 194 0.93 0.069 0.054 0.042* 0.015 0.855 [42]
    Swedish 430 0.819 < 0.001* 0.107 < 0.001* 0.074 0.017* [43]
    Russian 352 0.831 < 0.001* 0.119 < 0.001* 0.05 0.136 [44]
    Italian 157 0.796 < 0.001* 0.112 < 0.001* 0.092 0.007* [34]
    British 100 0.79 < 0.001* 0.125 < 0.001* 0.085 0.031* [45]
    Portuguese 135 0.788 < 0.001* 0.132 0.0002* 0.08 0.015* [46]
    Spanish 1076 0.766 < 0.001* 0.156 < 0.001* 0.078 0.012* [47]
    French 151 0.77 < 0.001* 0.15 < 0.001* 0.08 0.015* [48]
    Bolivian 778 0.922 0.034* 0.048 0.048* 0.03 0.410 [49]
    Cuban 132 0.72 < 0.001* 0.17 < 0.001* 0.11 0.002* [50]
    American 100 / / 0.08 0.011* 0.06 0.124 [51]
    Croatian 200 0.74 < 0.001* 0.165 < 0.001* 0.095 0.005* [52]
    German 118 0.81 < 0.001* 0.14 < 0.001* 0.05 0.196 [53]
    Greek 283 / / 0.129 < 0.001* 0.081 0.012* [54]
    Belgian 121 0.822 < 0.001* 0.1 0.001* 0.074 0.050* [37]
*

Indicated P < 0.05.

Ref: Reference.