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Accumulated collagen deposited in the myocardial interstitial of AF patients with RHD. A. Masson staining in right atrium of SR and AF patients with rheumatic heart disease (Representative image, collagen was stained for blue). B. Quantification of the total collagen volume in SR and AF patients with rheumatic heart disease. C. The mRNA levels of CTGF, Collagen I and III in the atrial tissues of SR and AF patients with rheumatic heart disease. *P<0.05 vs. SR group.
