Table 2.
Analysis of AEG-1 and Cyclin D1positive expression and related factors
| Related Factor | n | AEG-1 expressiona | P valueb | Cyclin D1 expressiona | P valueb | ||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| Negative (-) | Positive (+) | Negative (-) | Positive (+) | ||||
| Age | |||||||
| >65 | 58 | 21 (26.2) | 37 (63.8) | 0.46 | 23 (39.7) | 35 (60.3) | 0.291 |
| ≤65 | 27 | 12 (44.4) | 15 (55.6) | 14 (51.9) | 13 (48.1) | ||
| Gender | |||||||
| Male | 66 | 26 (39.4) | 40 (60.6) | 0.459 | 27 (40.9) | 39 (59.1) | 0.364 |
| Female | 19 | 7 (36.8) | 12 (63.2) | 10 (52.6) | 9 (47.4) | ||
| TNM stage | |||||||
| Superficial | 59 | 28 (47.5) | 31 (52.5) | 0.014 | 31 (52.5) | 28 (47.5) | 0.012 |
| Invasive | 26 | 5 (19.2) | 21 (80.8) | 6 (23.1) | 20 (76.9) | ||
| Recurrence | |||||||
| Negative | 48 | 25 (52.1) | 23 (47.9) | 0.004 | 26 (54.2) | 22 (45.8) | 0.024 |
| Positive | 37 | 8 (21.6) | 29 (78.4) | 11 (29.7) | 26 (70.3) | ||
| Grade | |||||||
| Low | 32 | 15 (46.9) | 17 (53.1) | 0.237 | 21 (65.6) | 11 (34.4) | 0.001 |
| High | 53 | 18 (34.0) | 35 (66.0) | 16 (30.2) | 37 (69.8) | ||
a
AEG-1 and Cyclin D1 protein expression, positive means IHS are 4-9, and negative means IHS are 0-3.
b
P values were evaluated by chi-square test.