Table 3.

Effects of atorvastatin on the expressions of different genes in monocytes/macrophages

	Atorvastatin 80 mg (n=24)			Atorvastatin 20 mg (n=23)			P
	Baseline	Week 6	Week 12	Baseline	Week 6	Week 12	Time	Dosage	Interactions
Tp53	0.27±0.05	0.25±0.03	0.35±0.06	0.20±0.05	0.17±0.03	0.21±0.06	0.358	0.015	0.707
ATF4	0.82±0.04	0.84±0.04	0.74±0.03	0.80±0.04	0.85±0.04	0.78±0.03	0.038	0.737	0.643
CHOP	0.60±0.05	0.84±0.17	0.62±0.11	0.53±0.05	0.60±0.16	0.65±0.11	0.350	0.374	0.451
C/EBP	0.80±0.04	0.72±0.03	0.63±0.04	0.79±0.03	0.77±0.03	0.73±0.04	0.003	0.088	0.244
TRIB3	0.80±0.05	0.74±0.05	0.86±0.08	0.72±0.05	0.70±0.05	0.74±0.08	0.358	0.045	0.717

Notes: Data are means ± SEM. Abbreviations: Tp53, tumor protein 53; ATF4, activating transcription factor 4; C/EBP, CCAAT/enhancer binding protein; CHOP, C/EBP homologous protein; TRIB3, Tribbles 3.