Table 4.
Comparison of the accuracy of pre-operative N staging in colorectal cancer using PET-CT and/or PET
| Diagnostic Method | Number of study | Diagnostic Threshold | Pooled Sensitivity | Pooled Specificity | Positive LR | Negative LR | Pooled DOR | AUC | Q* |
|---|---|---|---|---|---|---|---|---|---|
| PET-CT/PET | 20 | Yes | 0.62 (0.59-0.66) | 0.70 (0.67-0.73) | 2.83 (1.96-4.06) | 0.60 (0.50-0.71) | 6.14 (3.80-9.91) | 0.7594 | 0.7012 |
| PET | 8 | No | 0.36 (0.29-0.44) | 0.93 (0.89-0.96) | 4.22 (2.22-8.03) | 0.72 (0.59-0.88) | 7.05 (2.93-17.01) | 0.8559 | 0.7868 |
| PET-CT | 12 | Yes | 0.70 (0.66-0.74) | 0.63 (0.59-0.67) | 2.38 (1.64-3.45) | 0.52 (0.42-0.65) | 5.81 (3.26-10.34) | 0.7691 | 0.7094 |
PET, Positron Emission Tomography; CT, Computed Tomography; LR, Likelihood Ratio; DOR, Diagnostic Odds Ratio; AUC, area under the curve.