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. 2015 Nov 15;8(11):21886–21892.

Table 1.

Characteristics of studies evaluating the effects of TGF-β1 polymorphisms on DM risk

First author, year Ethnicity DM Controls M allele (%) HWE




MM MN NN Total MM MN NN Total Case Control P
TGF-β1 codon 10 C/T1
    Tsiavou, 20044 Caucasian 9 11 12 32 7 24 8 39 45.3 48.7 0.351
    Buraczynska, 20074 Caucasian 126 224 153 503 76 181 143 400 47.3 41.6 0.387
    Javor, 20103 Caucasian 17 56 75 148 27 71 41 139 30.4 44.9 0.931
    Jahromi, 20103 Caucasian 78 208 102 388 75 80 74 229 46.9 50.2 < 10-4
    El-Sherbini, 20134 Caucasian 10 50 39 99 3 27 68 98 34.3 35.1 0.332
    Bazzaz, 20143 Caucasian 39 126 83 248 15 57 47 119 41.1 36.5 0.383
TGF-β1 codon 25 G/C2
    Tsiavou, 20044 Caucasian 26 6 0 32 35 4 0 39 90.6 94.9 0.945
    Javor, 20103 Caucasian 137 11 0 148 117 22 0 139 96.3 92.1 0.599
    El-Sherbini, 20134 Caucasian 79 20 0 99 81 9 8 98 89.9 87.2 < 10-4
    Bazzaz, 20143 Caucasian 201 44 3 248 97 21 1 119 90 90.3 0.905
1

C/T = M/N;

2

G/C = M/N;

3

Type 1 diabetes;

4

Type 2 diabetes.