Table 1.
First author, year | Ethnicity | DM | Controls | M allele (%) | HWE | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
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MM | MN | NN | Total | MM | MN | NN | Total | Case | Control | P | ||
TGF-β1 codon 10 C/T1 | ||||||||||||
Tsiavou, 20044 | Caucasian | 9 | 11 | 12 | 32 | 7 | 24 | 8 | 39 | 45.3 | 48.7 | 0.351 |
Buraczynska, 20074 | Caucasian | 126 | 224 | 153 | 503 | 76 | 181 | 143 | 400 | 47.3 | 41.6 | 0.387 |
Javor, 20103 | Caucasian | 17 | 56 | 75 | 148 | 27 | 71 | 41 | 139 | 30.4 | 44.9 | 0.931 |
Jahromi, 20103 | Caucasian | 78 | 208 | 102 | 388 | 75 | 80 | 74 | 229 | 46.9 | 50.2 | < 10-4 |
El-Sherbini, 20134 | Caucasian | 10 | 50 | 39 | 99 | 3 | 27 | 68 | 98 | 34.3 | 35.1 | 0.332 |
Bazzaz, 20143 | Caucasian | 39 | 126 | 83 | 248 | 15 | 57 | 47 | 119 | 41.1 | 36.5 | 0.383 |
TGF-β1 codon 25 G/C2 | ||||||||||||
Tsiavou, 20044 | Caucasian | 26 | 6 | 0 | 32 | 35 | 4 | 0 | 39 | 90.6 | 94.9 | 0.945 |
Javor, 20103 | Caucasian | 137 | 11 | 0 | 148 | 117 | 22 | 0 | 139 | 96.3 | 92.1 | 0.599 |
El-Sherbini, 20134 | Caucasian | 79 | 20 | 0 | 99 | 81 | 9 | 8 | 98 | 89.9 | 87.2 | < 10-4 |
Bazzaz, 20143 | Caucasian | 201 | 44 | 3 | 248 | 97 | 21 | 1 | 119 | 90 | 90.3 | 0.905 |
C/T = M/N;
G/C = M/N;
Type 1 diabetes;
Type 2 diabetes.