Table 2.
Flow of the samples within the cohort of 400 patients where molecular subtype was determined (N=400)
| Protein expression level assessed | Number of samples | Number of positive samples (%) | System activation assessed | Number of samples | Number of positive samples (%) |
|---|---|---|---|---|---|
| PTEN | 399 | 279 (69.9%) | ERBB/PI3K pathway | 396 | 106 (26.8%) |
| ERBB1 | 399 | 166 (41.6%) | |||
| HER2 | 400 | 147 (36.8%) | |||
| ERBB3 | 400 | 141 (35.3%) | |||
| ERBB4 | 400 | 395 (98.8%) | |||
| PI3K | 400 | 7 (1.8%) | |||
| pAKT1 | 397 | 325 (81.9%) | |||
| STMN1 | 400 | 156 (39.0%) | |||
| TP53 | 400 | 160 (40.0%) | TP53 system | 400 | 160 (40.0%) |
| MLH1 | 399 | 13 (3.3%) | Mismatch Repair system | 399 | 93 (23.3%) |
| MSH2 | 400 | 90 (22.5%) |