Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pathway activation in the context of molecular subtypes
| Molecular subtype | Number of positive samples (%) | ||
|---|---|---|---|
|
| |||
| Activation of ERBB/PI3K pathway | Mismatch Repair system functioning | TP53 mutated | |
| PR+/ER+/HER2+ | 73/127 (57.5%) | 43/128 (33.6%) | 78/129 (60.5%) |
| PR+/ER+/HER2- | 29/222 (13.1%) | 37/224 (16.5%) | 50/224 (22.3%) |
| PR-/ER-/HER2+ | 4/18 (22.2%) | 6/18 (33.3%) | 15/18 (83.3%) |
| PR-/ER-/HER2- | 0/29 (0%) | 7/29 (24.1%) | 17/29 (58.6%) |
| P value (chi square) | <0.00001 | 0.002 | <0.000001 |
