Table 2.
Stroke lesion locations associated with somatosensory deficits.
| Tested symptom | MNI coordinates (mm) |
Brain region | Z-score | ||
|---|---|---|---|---|---|
| X | Y | Z | |||
| Light touch | 29 | − 25 | 25 | Superior thalamocortical radiation | 7.2** |
| 34 | − 7 | 18 | S2/parietal operculum | 7.1** | |
| 34 | − 14 | 16 | Insulo-opercular cortex | 6.8** | |
| 29 | − 23 | 25 | STR | 6.6** | |
| 33 | − 5 | 13 | External capsule | 6.2** | |
| 33 | − 19 | 21 | S2/parietal operculum | 5.1** | |
| 35 | − 15 | 16 | S2/parietal operculum | 3.9** | |
| 42 | − 35 | 27 | Inferior parietal lobule | 3.9** | |
| 28 | − 21 | 12 | CST | 3.5** | |
| 28 | − 5 | 10 | Putamen | 3.2** | |
| 27 | − 19 | 14 | Posterior limb of internal capsule | 3.1** | |
| Pressure | 34 | − 14 | 16 | Insulo-opercular cortex | 4.9** |
| 29 | − 25 | 25 | STR | 4.8** | |
| 32 | − 22 | 23 | S2/parietal operculum | 4.0** | |
| 35 | 2 | 2 | External capsule | 3.7** | |
| 29 | − 21 | 12 | Posterior limb of internal capsule | 3.4** | |
| 37 | − 12 | 12 | Insular cortex | 3.1** | |
| 46 | − 14 | 18 | S2/parietal operculum | 3.1** | |
| 28 | − 21 | 12 | CST | 3.1** | |
| 30 | − 6 | 12 | Putamen | 2.7** | |
| Pinprick | 32 | − 22 | 23 | S2/parietal operculum | 4.3** |
| 29 | − 25 | 25 | STR | 4.3** | |
| 34 | − 15 | 16 | Insulo-opercular cortex | 4.2** | |
| 29 | − 21 | 23 | CST | 3.7** | |
| 42 | − 35 | 27 | Inferior parietal lobule | 3.7** | |
| 29 | − 21 | 12 | Posterior limb of internal capsule | 3.1** | |
| 35 | 2 | 2 | External capsule | 2.6** | |
| Proprioception | 32 | − 20 | 15 | S2/parietal operculum | 4.6** |
| 29 | − 25 | 25 | STR | 4.6** | |
| 34 | − 14 | 16 | Insulo-opercular cortex | 4.4** | |
| 32 | − 21 | 17 | S2/parietal operculum | 3.9** | |
| 27 | − 21 | 24 | CST | 3.7** | |
| PTT | 34 | − 14 | 15 | Insulo-opercular cortex | − 4.0++ |
| 34 | − 6 | 15 | S2/parietal operculum | − 3.9++ | |
| 31 | − 22 | 18 | S2/parietal operculum | − 3.9++ | |
| 29 | − 24 | 25 | STR | − 3.5++ | |
| 36 | − 13 | 2 | External capsule | − 3.2++ | |
| 31 | 5 | 5 | Putamen | − 3.0++ | |
| SSEP | 30 | − 12 | 14 | S2/parietal operculum | − 3.7+ |
| 29 | − 24 | 25 | STR | − 3.7+ | |
| 34 | − 17 | 16 | S2/parietal operculum | − 3.4+ | |
| 29 | − 16 | 12 | Posterior limb of internal capsule | − 3.2+ | |
| 35 | 3 | 2 | External capsule | − 2.3+ | |
PTT = perceptual threshold of touch, SSEP = somatosensory evoked potentials, S2 = secondary somatosensory cortex, STR = superior thalamocortical radiation, CST = corticospinal tract. All given brain regions are corrected for multiple comparison. If indicated with two asterisks (**), the voxel is tested significant based on Brunner–Munzel Z-score after applying a FDR of 0.01. For dichotomous variables, Liebermeister Z-scores are indicated with a double cross (++) for FDR 0.01 or a single cross (+) for FDR 0.05.