Table 2. Association between estimated duration of diabetes and incidence of ischemic stroke.
| Non-Diabetic | Estimated Diabetes Duration < 3 years | Estimated Diabetes Duration ≥3 years | |
|---|---|---|---|
| Baseline Duration Values | |||
|
| |||
| Ischemic stroke events | 463 | 44 | 93 |
|
| |||
| Person-years (py) | 25,801.8 | 2299.9 | 2919.8 |
|
| |||
| Rate | 1.8/100 py | 1.9/100py | 3.2/100py |
|
| |||
| Among Diabetics Only | |||
|
| |||
| Hazard Ratio (unadjusted) | n/a | Reference | 1.75 (1.22-2.50) |
|
| |||
| Hazard Ratio (adjusted*) | n/a | Reference | 1.51 (1.05-2.17) |
|
| |||
| Among All Patients | |||
|
| |||
| Hazard Ratio (unadjusted) | Reference | 1.10 (0.81-1.50) | 1.80 (1.44-2.25) |
|
| |||
| Hazard Ratio (adjusted*) | Reference | 1.15 (0.84-1.58) | 1.63 (1.29-2.05) |
|
| |||
| Time Varying Duration Values | |||
| Ischemic stroke events | 463 | 21 | 116 |
| Person-years (py) | 25,801.8 | 1260.6 | 3959.1 |
| Rate | 1.8/100 py | 1.7/100 py | 2.9/100 py |
| Among Diabetics Only | |||
| Hazard Ratio (unadjusted) | n/a | Reference | 2.04 (1.27-3.26) |
| Hazard Ratio (adjusted*) | n/a | Reference | 1.74 (1.10-2.76) |
| Among All Patients | |||
| Hazard Ratio (unadjusted) | Reference | 0.84 (0.55-1.30) | 1.75 (1.43-2.15) |
| Hazard Ratio (adjusted*) | Reference | 0.90 (0.58-1.40) | 1.62 (1.31-2.00) |
*
Adjusted for age, gender, race, education, income, congestive heart failure, hypertension, prior ischemic stroke, coronary artery disease, and peripheral arterial disease
Py = person-years