Table 4.

Association of 32 GWA studies-derived SNP alleles with obesity in Chinese children

SNP	Nearest gene	Chr.	Allele		Obesity VS Normal-weight
			Effect	other	OR	95 % CI	Two-sided
							P-value
Speliotes et al. 2010 (in children and adults of European ancestry) [4]
rs1558902	FTO	16	A	T	1.31	1.01-1.69	0.039
rs2867125	TMEM18	2	C	T	1.06	0.79-1.42	0.703
rs571312	MC4R	18	A	C	1.16	0.94-1.42	0.166
rs10938397	GNPDA2	4	G	A	1.19	0.98-1.43	0.077
rs10767664	BDNF	11	A	T	1.10	0.93-1.30	0.273
rs2815752	NEGR1	1	A	G	1.07	0.79-1.46	0.645
rs7359397	SH2B1	16	T	C	1.06	0.85-1.34	0.597
rs9816226	ETV5	3	T	A	0.90	0.56-1.45	0.669
rs3817334	MTCH2	11	T	C	1.05	0.88-1.25	0.626
rs29942	KCTD15	19	C	T	1.01	0.83-1.23	0.949
rs543874	SEC16B	1	G	A	1.41	1.15-1.73	0.001
rs987237	TFAP2B	6	G	A	1.27	1.02-1.59	0.032
rs7138803	FAIM2	12	A	G	1.06	0.87-1.30	0.542
rs713586	RBJ	2	C	T	1.19	1.00-1.42	0.048
rs2241423	MAP2K5	15	G	A	1.34	1.12-1.59	0.001
rs2287019	QPCTL	19	C	T	0.89	0.72-1.10	0.283
rs1514175	TNNI3K	1	A	G	1.11	0.90-1.36	0.332
rs2112347	FLJ35779	5	T	G	1.02	0.85-1.21	0.865
rs16912921	LRRN6C	9	A	C	0.95	0.79-1.15	0.628
rs3810291	TMEM160	19	A	G	0.93	0.77-1.12	0.456
rs1555543	PTBP2	1	C	A	0.84	0.65-1.08	0.174
rs9579083	MTIF3	13	C	G	1.08	0.85-1.37	0.519
rs4929949	RPL27A	11	C	T	0.90	0.75-1.07	0.215
rs206936	NUDT3	6	G	A	0.99	0.83-1.18	0.919
Scherag et al. 2010 (in children and adults of European ancestry)[6]
rs12145833	SDCCAG8	1	T	G	0.96	0.71-1.31	0.799
rs13278851	TNKS/MSRA	8	A	G	0.90	0.71-1.14	0.375
Bradfield et al. 2012 (in children of European ancestry) [5]
rs9568856	OLFM4	13	A	G	1.08	0.89-1.30	0.438
rs9299	HOXB5	17	A	G	1.07	0.90-1.27	0.449
Okada et al. 2012 (in East Asians) [8]
rs2206734	CDKAL1	6	G	A	1.21	1.01-1.44	0.035
rs11142387	KLF9	9	C	A	0.90	0.75-1.08	0.268
Wen et al. 2012 (in East Asians) [7]
rs261966	PCSK1	5	G	A	1.03	0.87-1.22	0.764
rs12597579	GP2	16	C	T	1.02	0.84-1.24	0.871

SNP alleles which are associated with obesity risk in Chinese children are highlighted in bold. Chr. Chromosome