Fig. 6.

miR-483-3p sponge rescues SRF expression in EPCs. a Schematic graph of miRNA construction. b Binding sites of miR-483-3p sponge. c The relative expression of miR-483-3p after infection with lenti-vector control, lenti-483-3p and lenti-483-3p sponge. The relative expression data were normalized to the amount of U6, and expressed as mean ± SEM (n = 3, *P < 0.05 vs. lenti-vector; ***P < 0.001 vs. lenti-vector; ^###P < 0.001 vs. lenti-483-3p). d SRF protein level was significantly increased after miR-483-3p sponge treatment. Each bar represents mean values ± SEM (n = 3, *P < 0.05 vs. lenti-vector; **P < 0.01 vs. lenti-vector)