TABLE IV.
Effect of sensorineural hearing loss on task-specific subtests of intelligence and neurocognitive function
| Neurocognitive Test | N (%) | Coeff1 | [95% CI] | P | Additional Significant Covariates included in model2 |
|---|---|---|---|---|---|
| Verbal Comprehension Index | |||||
| Similarities or Word Reasoning | 46 (79) | −2.20 | [−4.39, −0.01] | 0.049 | ethnicity, diagnosis |
| Vocabulary/ Receptive Vocabulary | 49 (85) | −2.44 | [−4.19, −0.70] | 0.007 | ethnicity, diagnosis |
| Perceptual Reasoning Index/Performance | |||||
| Block Design | 49 (85) | −3.45 | [−5.23, −1.66] | 0.001 | duration to neurocognitive testing |
| Matrix Reasoning | 40 (69) | −1.90 | [−4.16, 0.35] | 0.095 | None |
| Working Memory Index | |||||
| Digit Span | 38 (66) | −3.54 | [−5.23, −1.86] | <0.001 | ethnicity |
| Processing Speed Index | |||||
| Coding | 43 (74) | −3.11 | [−5.09, −1.13] | 0.003 | none |
| Symbol Search | 42 (72) | −2.82 | [−5.09, −0.56] | 0.016 | none |
1
Coefficient represents Stepwise linear regression models constructed for above neurocognitive tests, significance set at α<0.05 (bolded). See statistical methods for additional details.
2
Base model includes age at diagnosis, history of hematopoietic stem cell transplant, history of posterior fossa syndrome, radiation dose [Gy] to whole brain, and additional radiation dose [Gy] to posterior fossa. Additional included covariates indicated.
Cddp = cisplatinum