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. Author manuscript; available in PMC: 2016 Jun 10.
Published in final edited form as: Genes Immun. 2015 Dec 10;17(1):66–74. doi: 10.1038/gene.2015.56

Figure 2.

Figure 2

ProI SNPs in predicted binding sites alter transcription factor binding. (a) EMSA analysis of the predicted AP-1 binding region. Jurkat nuclear lysates were incubated with the oligonucleotides shown below. Predicted AP1-binding sites are underlined, and nucleotide differences are in bold type. The bands corresponding to an AP1 complex are indicated by arrows. (b) EMSA analysis of the tandem Oct and Ets sites in Jurkat nuclear lysates. Oligonucleotide probes are shown below with Oct and Ets sites underlined, and nucleotide differences in bold type. Oct-1 and Elf-1 complexes are indicated by arrows.