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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Synapse. 2015 Dec 24;70(3):98–111. doi: 10.1002/syn.21877

Fig. 7.

Fig. 7

Panel A: Saturation binding of [3H](+)-pentazocine to CD-1® mouse brain membranes at 37 ºC with a 180 min incubation and haloperidol (1.0 μM) to define non-specific binding. Panel B: Saturation isotherm for [3H]DTG binding to CD-1® mouse brain membranes at 25 ºC with a 60 min incubation, 500 nM (+)-pentazocine to mask σ1 binding, and haloperidol (10.0 μM) to define non-specific binding. Open diamonds show specific binding, while open circles depict the inset Rosenthal plots. Data are representative experiments performed in duplicate, and replicated 4 – 6 times.