Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dosing and Schedule of Dexamethasone, Thalidomide, Panobinostat, Cyclophosphamide, and Carfilzomib (DT-PACK) Combination Regimen
| Dexamethasone 40mg/day oral once-daily with food on days 1,8,15 once weekly |
| Thalidomide 400mg/day oral once-daily days 1-28 |
| Panobinostat 20 mg oral three times a week |
| Cyclophosphamide 300mg oral once-daily with food on days 1,8,15 |
| Carfilzomib 27mg/m2/day IV infusion over 30 minutes days 1, 2, 8, 9, 15, 16 |
Cycle length = 28 days
