Table 3.
Patient characteristics
| Hospital | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | B | Cd | D | E | F | G | ||||||||
| Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | |
| Males with primary CDI, n (%) | 38/66 (57.6%) | 15/32 (46.9%) | 52/98 (53.1%) | 33/64 (51.6%) | 30/79 (38.0%) | 61/140 (43.6%) | 32/70 (45.7%) | 19/56 (33.9%) | 64/116 (55.2%) | 35/93 (37.6%), p=0.01 | 27/89 (30.3%) | 35/89 (39.3%) | 43/112 (38.4%) | 31/69 (44.9%) |
| Median age at primary CDI (years) | 70.0 (n=66) | 77.5 (n=32) | 77.0 (n=98) | 76.0 (n=64) | 78.0 (n=78) | 74.0 (n=140), p=0.05 | 78.5 (n=70) | 79.0 (n=56) | 78.0 (n=112) | 75.0 (n=93) | 81.0 (n=89) | 80.0 (n=89) | 81.0 (n=112) | 77.0 (n=69), p=0.05 |
| Median age at recurrence (years) | 82.0 (n=7) | 43.5 (n=2), p=0.05 | 77.0 (n=17) | 77.5 (n=2) | 83.0 (n=5) | 75.5 (n=30), p<0.05 | 83.0 (n=5) | 83.0 (n=1) | 69.0 (n=20) | 70.0 (n=12) | 82.0 (n=16) | 80.0 (n=11) | 78.0 (n=9) | 84.5 (n=4) |
| Patients with severe/complicated primary CDI, n (%)b | 15/55 (27.3%) | 13/18 (72.2%), p<0.01 | NAa | NAa | 13/49 (26.5%) | 35/88 (39.8%) | 14/64 (21.9%) | 11/51 (21.6%) | 14/75 (18.7%) | 5/31 (16.1%) | 2/27 (7.4%) | 11/64 (17.2%) | 44/102 (43.1%) | 34/65 (52.3%) |
| Patients with antibiotics before CDI (primary), n (%)b | 47/58 (81.0%) | 26/30 (86.7%) | NAa | NAa | 62/74 (83.8%) | 121/134 (90.3%) | 53/63 (84.1%) | 40/49 (81.6%) | 83/112 (74.1%) | 73/91 (80.2%) | 68/80 (85.0%) | 64/86 (74.4%) | 80/87 (92.0%) | 53/54 (98.1%) |
| Patients with PPI use (primary), n (%)b | 32/57 (56.1%) | 11/26 (42.3%) | NAa | NAa | 47/60 (78.3%) | 85/114 (74.6%) | 38/57 (66.7%) | 32/49 (65.3%) | 53/115 (46.1%) | 35/83 (42.2%) | 0/46 (0.0%) | 41/83 (49.4%), p<0.01 | 45/75 (60.0%) | 27/49 (55.1%) |
| Patients with long stayc in health care (primary), n (%)b | 17/54 (31.5%) | 11/27 (40.7%) | 32/78 (41.0%) | 31/54 (57.4%) | 33/76 (43.4%) | 57/133 (42.9%) | 33/56 (58.9%) | 22/53 (41.5%) | 55/115 (47.8%) | 33/93 (35.5%) | 42/89 (47.2%) | 35/88 (39.8%) | 36/108 (33.3%) | 20/50 (40.0%) |
| Patients with pre-CDI ICU stay (primary), n (%)b | 8/66 (12.1%) | 5/32 (15.6%) | NAa | NAa | 3/79 (3.8%) | 10/139 (7.2%) | 5/70 (7.1%) | 2/56 (3.6%) | 6/115 (5.2%) | 2/93 (2.2%) | 1/86 (1.2%) | 0/89 (0.0%) | 0/112 (0.0%) | 3/69 (4.3%), p<0.05 |
| Patients with community-acquired CDI (primary), n (%)b | 21/66 (31.8%) | 14/32 (43.8%) | 34/98 (34.7%) | 18/64 (28.1%) | 23/78 (29.5%) | 41/140 (29.3%) | 13/70 (18.6%) | 15/56 (26.8%) | 28/112 (25.0%) | 30/93 (32.3%) | 36/89 (40.4%) | 25/89 (28.1%) | 50/112 (44.6%) | 27/69 (39.1%) |
aNot available
bNumbers refer to CDI episodes
cSeven days or longer
dData from a sample of all episodes