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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Biotechnol J. 2015 Sep 10;10(10):1529–1545. doi: 10.1002/biot.201400758

Figure 2.

Figure 2

Schematic of the bone marrow niche. HSCs are known to localize within discrete microenvironments across the marrow which present a wide range of biophysical and biomolecular cues. The endosteal niche, associated closer to the trabecular bone is home to more quiescent HSCs whereas the perivascular niche houses more actively cycling HSCs.